KAWASAKI SYNDROME

Wisconsin Division of Public Health Disease Surveillance Manual (EpiNet, February 2005)

I. IDENTIFICATION

A. CLINICAL DESCRIPTION: An acute febrile syndrome of early childhood, presumably of infectious or toxin origin, clinically characterized by a high spiking fever unresponsive to antibiotics with pronounced irritability and mood change.

B. REPORTING CRITERIA: Clinical diagnosis.

C. WISCONSIN CASE DEFINITION: A febrile illness of ³ 5 days duration with at least four of the five following physical problems and no other more reasonable explanation for the observed clinical findings.

1. Bilateral conjunctival injection.
2. Oral changes (erythema of lips or oropharynx, strawberry tongue or fissuring of the lips).
3. Peripheral extremity changes (edema, erythema, generalized or periungual desquamation).
4. Rash.
5. Cervical lymphadenopathy (at least one lymph node ³ 1.5 cm in diameter).

NOTE: If fever disappears after intravenous gamma globulin is started, fever may be of < 5 days duration, and the clinical case definition may still be met.

II. ACTIONS REQUIRED / PREVENTION MEASURES

A. WISCONSIN DISEASE SURVEILLANCE CATEGORY II: Report to the patient's local health officer on an Acute and Communicable Disease Case Report (DPH 4151) or other means within 72 hours of the identification of a case or suspected case.

B. EPIDEMIOLOGY REPORTS REQUESTED:

1. Acute and Communicable Disease Report (DPH 4151).
2. CDC Kawasaki Syndrome Case Report Form (CDC 55.54).

III. CONTACTS FOR CONSULTATION

A. BCDP / COMMUNICABLE DISEASE EPIDEMIOLOGY SECTION: (608) 266-5326.

B. REGIONAL STAFF: See Epinet Introduction: “REGIONAL OFFICE CONTACTS”.

IV. RELATED REFERENCES

1. “ Kawasaki Syndrome” DPH Disease Fact Sheet Series: View a list of all current Communicable Disease Fact Sheets

2. Heymann DL, ed. KAWASAKI SYNDROME. In: Control of Communicable Diseases Manual. 18 th ed. Washington , DC : American Public Health Association, 2004:287-289.

3. Pickering LK, ed. Kawasaki Syndrome. In: Red Book: 2003 Report of the Committee on Infectious Diseases. 26 th ed. Elk Grove Village , IL : American Academy of Pediatrics, 2003:392-395.

 V. DISEASE TRENDS

CENTERS FOR DISEASE CONTROL / KAWASAKI SYNDROME Form here